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Napro-A Plus 500 Tablet is a combination medicine (Esomeprazole + Naproxen) that helps in relieving pain. It is used to relieve pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.
You are recommended to avoid alcohol consumption with Napro-A Plus 500 Tablet as it may increase the risk of stomach bleeding and ulcer.
There is limited data on how Napro-A Plus 500 Tablet affects pregnancy. Please consult your doctor if you are planning to become pregnant or already pregnant before starting Napro-A Plus 500 Tablet.
Napro-A Plus 500 Tablet passes into the breast milk. However, no evidence of risk has been reported. Please consult your doctor before intake of Napro-A Plus 500 Tablet. Your doctor will weigh the benefits and any potential risks before prescribing Napro-A Plus 500 Tablet to you.
Napro-A Plus 500 Tablet may cause dizziness, tiredness, drowsiness, or vision problems in some people. So, drive only if you are alert after taking Napro-A Plus 500 Tablet.
Napro-A Plus 500 Tablet is not recommended for use in patients with moderate to severe and severe renal impairment. The dose may be adjusted by your doctor as required. So, it should be used only when prescribed by your doctor.
Napro-A Plus 500 Tablet is to be used with caution in people having liver diseases. Dose adjustments may be necessary. So, you should use it only with your doctor's prescription.
Napro-A Plus 500 Tablet blocks the release of a substance called prostaglandin in the body. Prostaglandins are responsible for the signs of inflammation such as pain and fever. This anti-inflammatory action is useful in the reduction of pain, stiffness, swelling, and fever connected with inflammation.
It is used to relieve pain in the following conditions:
The pill consists of two parts: a quick-release coating of Esomeprazole Magnesium and an enteric-coated Naproxen core. This design allows for the release of Esomeprazole into the stomach first, followed by the release of Naproxen in the small intestine.
Naproxen is a type of nonsteroidal anti-inflammatory drug (NSAID) that has both pain-relieving and fever-reducing properties. It functions by inhibiting the production of prostaglandins. Esomeprazole, on the other hand, is a proton pump inhibitor that suppresses the secretion of gastric acid by blocking the H+/k+ -ATPase in the parietal cell of the stomach. By acting specifically on the proton pump, Esomeprazole decreases gastric acidity by inhibiting the final stage of acid production.
Take Napro-A Plus 500 Tablet as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.
Napro-A Plus 500 Tablet may interact with several medications, including anti-inflammatory drugs, blood thinners, steroids, diuretics, heart and blood pressure medications, antidepressants, and rheumatoid arthritis drugs. It may also interact with alcohol, increasing the risk of stomach bleeding, drowsiness, and dizziness. Individuals with diabetes, stomach ulcer, gastrointestinal bleeding, asthma, kidney, liver, or heart problems, and autoimmune conditions like systemic lupus erythematosus, colitis, or Crohn's disease should consult a doctor before taking Napro-A Plus 500 Tablet. It is important to inform your healthcare provider of all the medications, supplements, and medical conditions before taking Napro-A Plus 500 Tablet to prevent any potential interactions or adverse effects.
The use of Napro-A Plus 500 Tablet is contraindicated in individuals who have a hypersensitivity to any of the tablet's ingredients or substituted benzimidazoles. Napro-A Plus 500 Tablet should not be taken if an individual has a history of asthma, urticaria, or other allergic responses after taking aspirin or other NSAIDs.
Furthermore, the use of Napro-A Plus 500 Tablet during the peri-operative period of coronary artery bypass graft (CABG) surgery is not recommended. This is because it can increase the risk of bleeding and other complications during and after the surgery.
Category C pregnancy. It should be avoided in late pregnancy since it may cause premature closure of the ductus arteriosus. Because of the Naproxen component, this tablet should not be taken by nursing mothers.
Protect from light and moisture by storing at a temperature below 30°C. Keep out of children's reach.
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